• sense clinically
  • think mechanistically
  • act interdisciplinarily
  • treat innovatively

Dr. Philipp Mertins

Technology Platforms Proteomics
Max-Delbrück Center for Molecular Medicine (MDC)
Robert-Rössle-Str. 10
13092 Berlin

E-Mail: Philipp.Mertins(at)mdc-berlin.de

Scientific Scope

Our platform provides high-throughput techniques for studying the basic function and regulation of proteins in health and disease. This helps to identify new candidates for novel diagnostic and therapeutic approaches.

Proteomics enables the global and targeted analysis of all proteins and their functional states. Proteins are central to most biological functions within an organism and frequently alter in their abundance and in their activation status in disease. Thus, proteins are routinely used as disease biomarkers as well as drug targets.

To elucidate how proteins work, proteomics approaches make use of mass spectrometers. These high-throughput instruments allow proteins extracted from cells, tissues, and blood samples to be identified and quantified. In addition, it is possible to explore the binding partners of proteins, their localization in cells and tissues, and their functional activity.

Selected References