Prof. Dr. rer. nat. Gerhard Wolber
Molecular Design Lab
Freie Universität Berlin
Institut für Pharmazie
Königin-Luise-Str. 2+4
Room 275 Vorderhaus
14195 Berlin
Tel: +49 30 838 52686
Fax: +49 30 838 452686
E-Mail: gerhard.wolber(at)fu-berlin.de
http://www.drug-design.de/
Selected References
- Sribar D, Grabowski M, Murgueitio MS, Bermudez M, Weindl G and Wolber G. Identification and characterization of a novel chemotype for human TLR8 inhibitors. Eur J Med Chem. 2019;179:744-752.
- Schaller D, Sribar D, Noonan T, Deng LH, Nguyen TN, Pach S, Machalz D, Bermudez M and Wolber G. Next generation 3D pharmacophore modeling.WIREs-Computational Molecular Science. 2020;10:e1468.
- Tauber C, Wamser R, Arkona C, Tuegend M, Abdul Aziz UB, Pach S, Schulz R, Jochmans D, Wolber G, Neyts J and Rademann J. Chemical evolution of antivirals against enterovirus D68 through protein-templated Knoevenagel reactions. Angew Chem Int Ed. 2021;60:13294-13301
- Becker D, Kaczmarska Z, Arkona C, Schulz R, Tauber C, Wolber G, Hilgenfeld R, Coll M and Rademann J. Irreversible inhibitors of the 3C protease of Coxsackie virus through templated assembly of protein-binding fragments. Nat Commun. 2016;7:12761
- Holze J, Bermudez M, Pfeil EM, Kauk M, Bödefeld T, Irmen M, Matera C, Dallanoce C, De Amici M, Holzgrabe U, König GM, Tränkle C, Wolber G, Schrage R, Mohr K, Hoffmann C, Kostenis E and Bock A. Ligand-Specific Allosteric Coupling Controls G-Protein-Coupled Receptor Signaling. ACS Pharmacology & Translational Science. 2020;3:859-867