PD Dr. Angela Relogio

Systems Biology of Cancer
Molecular Cancer Research Center (MKFZ)
Institute for Theoretical Biology (ITB)
Charité - Universitätsmedizin Berlin

http://sysbio-relogio.com/

 

University Education

  • Habilitation in Molecular Biology and Bioinformatics, Charité Medical University of Berlin, Germany
  • Joint PhD in Biomedical Sciences, European Molecular Biology Laboratory, Heidelberg, Germany and the Faculty of Medicine, University of Lisbon
  • Diploma in Technological-Physics Engineering, Superior Technical Institute, University of Lisbon, Portugal

Professional Experience (selection)

  • Research coordinator of the Institute for Theoretical Biology (ITB) at the Charité-Universitätsmedizin Berlin
  • Teaching Coordinator of the Institute for Theoretical Biology (ITB) at the Charité-Universitätsmedizin Berlin
  • Group leader (Charité - Universitätsmedizin Berlin)
  • Post-Doctoral fellow (European Molecular Biology Laboratory (EMBL), Heidelberg
  • PhD student (European Molecular Biology Laboratory (EMBL), Heidelberg

Scientific Scope

  • Mathematical modelling of the mammalian circadian clock
  • Regulation of alternative splicing
  • Systems biology of cancer
  • Circadian regulation of molecular processes
  • Development of in silico and in vitro models for chronotherapy

Most important Awards, Grants or Scientific Achievements

  • Female Independency Award (FIA) from the Berlin School of Integrative Oncology (BSIO), Charité Medical University of Berlin, Germany.
  • Young Investigator’s Group – Grant from the BMBF, Germany.
  • Rahel-Hirsch-excellence award, Charité Medical University of Berlin, Germany.                      
  • Postdoctoral fellowship from the European Molecular Biology Laboratory (EMBL), Germany.
  • PhD fellowship-Praxis XXI programme from the Foundation for Science and Technology, Ministry for Science and Technology, Portugal and the European Molecular Biology Laboratory (EMBL), Germany.

Selected References

  • Abreu M, Basti A, Genov N, Mazzoccoli G, Relógio A* (2018) The reciprocal interplay between TNFα and the circadian clock impacts on cell proliferation and migration in Hodgkin lymphoma cells. Sci Rep. 
  • Fuhr L, El-Athman R, Scrima R, Cela O, Carbone A, Knoop H, Li Y, Hoffmann K, Laukkanen MO, Corcione F, Steuer R, Meyer TF, Mazzoccoli G, Capitanio N, Relógio A* (2018) The Circadian Clock Regulates Metabolic Phenotype Rewiring Via HKDC1 and Modulates Tumor Progression and Drug Response in Colorectal Cancer. EBioMedicine
  • El-Athman R, Fuhr L, Relógio A* (2018) A Systems-Level Analysis Reveals Circadian Regulation of Splicing in Colorectal Cancer. EBioMedicin
  • El-Athman R, Fuhr L, Relógio A* (2018) A Systems-Level Analysis Reveals Circadian Regulation of Splicing in Colorectal Cancer. EBioMedicin
  • Lehmann R, Childs L, Thomas P, Abreu M, Fuhr L, Herzel H, Leser U, Relógio A* (2015). Assembly of a comprehensive regulatory network for the mammalian circadian clock: a bioinformatics approach. PLOS One.