Prof. Dr. rer. nat. Thomas Blankenstein

University Education

• 1979-1983 Study of Biology, Universität Göttingen and Universität Köln
• 1983-1987 Ph.D. thesis ate the Institute of Genetics, Universität Köln
• 1991 Habilitation in Immunology, FU Berlin

Professional Experience (selection)

• 1994- Research group leaser at the MDC
• 1996-2000 Professor for "Molekulare Immunologie und Gentherapie", Faculty of BIology, FU Berlin

Research Fields

• i) Main field: Cancer immunology
• ii) Other fields: Cancer research, immunology

Most important Awards, Grants or Scientific Achievements

• 1991 German Cancer Award
• 2008-2010 DKH Grant
• 2005- Member of the European Society for Cancer Immunology and Immunotherapy

Selected References

• Poncette, L., Chen, X., Lorenz, F. and Blankenstein, T. (2019) "NY-ESO-1-specific MHC II restricted T cell receptors from antigen-negative hosts enhance tumor regression." J Clin Invest 129: 324-335.
• Kammertoens, K., Friese, C., Arina, A., Idel, C., Briesemeister, D., Rothe, M., Ivanov, A., Szymborska, A., Patone, G., Kunz, S., Sommermeyer, D., Engels, B., Leisegang, M., Textor, A., Fehling, H., Fruttiger, M., Lohoff, M., Herrmann, A., Yu, H., Weichselbaum, R., Uckert, W., Hübner, N., Gerhardt, H., Beule, D., Schreiber, H. and Blankenstein, T. (2017) "Tumour ischemia by Interferon-α- resembles physiological blood vessel regression." Nature 545: 98-102.
• Textor, A., Schmidt, K., Kloetzel, P., Weißbrich, B., Perez, C., Charo, J., Anders, K., Sidney, J., Sette, A., Schumacher, T., Keller, C., Busch, D., Seifert, U. and Blankenstein, T. (2016) "Preventing tumor escape by targeting a post-proteasomal trimming-independent epitope." J Exp Med 213: 2333-2348.
• Obenaus, M., Leitao, C., Leisegang, M., Chen, X., Gavvovidis, I., van der Bruggen, P., Uckert, W., Schendel, D. and Blankenstein, T. (2015) "Optimal-affinity T cell receptors against cancer antigens can be identified in antigen-negative hosts." Nat Biotechnol 33: 402-407.
• Li, L.P. and Blankenstein, T. (2013) "Generation of transgenic mice with megabase-sized human yeast artificial chromosomes by yeast spheroplast-embryonic stem cell fusion." Nat Protoc 8: 1567-1582.